Distinct roles of monkey OFC-subcortical pathways in adaptive behavior
Summary
The research team led by Group Leader Takafumi Minamimoto, Senior Researcher Kei Oyama (Natl. Inst. for Quantum Science and Technology) and Professor Masahiko Takada (Kyoto University) demonstrate the distinct contributions of different orbitofrontal cortex projections to various behavioral strategies, providing new insights into the neural basis of value-based adaptive decision-making in primates.
Their findings also have potential implications for understanding certain psychiatric disorders.
【Information on the outcome】
https://www.qst.go.jp/site/press/20240828.html (量子科学技術研究開発機構）
https://www.amed.go.jp/news/seika/2024_seika_index.html (AMED）
Article
＜Title＞
Distinct roles of monkey OFC-subcortical pathways in adaptive behavior
DOI: https://doi.org/10.1038/s41467-024-50505-8
＜Authors＞
Kei Oyama, Kei Majima, Yuji Nagai, Yukiko Hori, Toshiyuki Hirabayashi, Mark A. G. Eldridge, Koki Mimura, Naohisa Miyakawa, Atsushi Fujimoto, Yuki Hori, Haruhiko Iwaoki, Ken-ichi Inoue, Richard C. Saunders, Masahiko Takada, Noriaki Yahata, Makoto Higuchi, Barry J. Richmond & Takafumi Minamimoto
＜Journal＞
Nature Communications