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2023.02.17

Verification of the brain network marker of major depressive disorder for newly acquired data

Summary

A research group led by Associate Professor Go Okada and Professor Yasumasa Okamoto (Hiroshima University), Director Mitsuo Kawato and Senior Researcher Yuki Sakai (Advanced Telecommunications Research Institute International, ATR)  has developed a generalizable brain network marker for the diagnosis of major depressive disorder (MDD) across multiple imaging sites using resting-state functional magnetic resonance imaging. Here, they applied this brain network marker to newly acquired data to verify its test-retest reliability and anterograde generalization performance for new patients.

The results of this study reaffirmed the test-retest reliability and generalization performance of our brain network marker for the diagnosis of MDD.

【Information on the outcome】

https://www.hiroshima-u.ac.jp/news/75388 (広島大学)
https://www.atr.jp/topics/press_230213.html(ATR)
https://www.amed.go.jp/news/seika/2023_seika_index.html(AMED)

 

Article

<Title>

Verification of the brain network marker of major depressive disorder: test-retest reliability and anterograde generalization performance for newly acquired data
DOI : 10.1016/j.jad.2023.01.087

<Authors>

Go Okada, Toshinori Yoshioka, Ayumu Yamashita, Eri Itai, Satoshi Yokoyama, Toshiharu Kamishikiryo, Hotaka Shinzato, Yoshikazu Masuda, Yuki Mitsuyama, Shigeyuki Kan, Akiko Kurata, Masahiro Takamura, Atsuo Yoshino, Akio Mantani, Osamu Yamamoto, Norio Yokota, Tatsuji Tamura, Hiroaki Jitsuiki, Mitsuo Kawato, Okito Yamashita, Yuki Sakai, Yasumasa Okamoto

<Journal>

Journal of Affective Disorders